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Fingolimod additionally acts as immunomodulator focused on the innate immune system beyond its prominent effects on lymphocyte recirculation

Link
https://doi.org/10.1186/s12974-017-0817-6
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Multiple SkleroseMS Behandlung
Jahr
2017
Autoren
Thomas K, Sehr T, Proschmann U, Rodriguez-Leal FA, Haase R, Ziemssen T.
Verlag
J Neuroinflamm 2017;14(1).
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Safety and efficacy of opicinumab in acute optic neuritis (RENEW): a randomised, placebo-controlled, phase 2 trial

Link
https://doi.org/10.1016/s1474-4422(16)30377-5
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Multiple SkleroseMS Behandlung
Jahr
2017
Autoren
Cadavid D, Balcer L, Galetta S, Aktas O, Ziemssen T, Vanopdenbosch L, Frederiksen J, Skeen M, Jaffe GJ, Butzkueven H, Ziemssen F, Massacesi L, Chai Y, Xu L, Freeman S; RENEW Study Investigators.
Verlag
Lancet Neurol. 2017 Mar;16(3):189-199.
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Treatment effectiveness of alemtuzumab compared with natalizumab, fingolimod, and interferon beta in relapsing-remitting multiple sclerosis: a cohort study

Link
https://doi.org/10.1016/s1474-4422(17)30007-8
Tags
Multiple SkleroseMS Behandlung
Jahr
2017
Autoren
Kalincik T, Brown JWL, Robertson N, Willis M, Scolding N, Rice CM, Wilkins A, Pearson O, Ziemssen T, Hutchinson M, McGuigan C, Jokubaitis V, Spelman T, Horakova D, Havrdova E, Trojano M, Izquierdo G, Lugaresi A, Prat A, Girard M, Duquette P, Grammond P, Alroughani R, Pucci E, Sola P, Hupperts R, Lechner-Scott J, Terzi M, Van Pesch V, Rozsa C, Grand'Maison F, Boz C, Granella F, Slee M, Spitaleri D, Olascoaga J, Bergamaschi R, Verheul F, Vucic S, McCombe P, Hodgkinson S, Sanchez-Menoyo JL, Ampapa R, Simo M, Csepany T, Ramo C, Cristiano E, Barnett M, Butzkueven H, Coles A; MSBase Study Group.
Verlag
Lancet Neurol. 2017 Apr;16(4):271-281.
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Multiple sclerosis in the real world: A systematic review of fingolimod as a case study

Link
https://doi.org/10.1016/j.autrev.2017.02.007
Tags
Multiple SkleroseMS Behandlung
Jahr
2017
Autoren
Ziemssen T, Medin J, Couto CA, Mitchell CR.
Verlag
Autoimmun Rev 2017;16(4):355-376.
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Two studies in one: A propensity-score-matched comparison of fingolimod versus interferons and glatiramer acetate using real-world data from the independent German studies, PANGAEA and PEARL

Link
https://doi.org/10.1371/journal.pone.0173353
Tags
Multiple SkleroseMS Behandlung
Jahr
2017
Autoren
Alsop J, Medin J, Cornelissen C, Vormfelde SV, Ziemssen T.
Verlag
PLoS ONE 2017;12(5).
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Safety and in vivo immune assessment of escalating doses of oral laquinimod in patients with RRMS

Link
https://doi.org/10.1186/s12974-017-0945-z
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Multiple SkleroseMS Behandlung
Jahr
2017
Autoren
Ziemssen T, Tumani H, Sehr T, Thomas K, Paul F, Richter N, Samara E, Spiegelstein O, Sorani E, Bar-Ilan O, Mimrod D, Hayardeny L.
Verlag
J Neuroinflammation. 2017 Aug 31;14(1):172.
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To stop or not to stop disease modifying therapies in secondary progressive multiple sclerosis, that is the question

Link
https://doi.org/10.1080/14737175.2017.1340831
Tags
Multiple SkleroseMS Behandlung
Jahr
2017
Autoren
D'Amico E, Ziemssen T, Cottone S.
Verlag
Expert Rev Neurother 2017;17(9):847-849.
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Alemtuzumab in the long-term treatment of relapsing-remitting multiple sclerosis: An update on the clinical trial evidence and data from the real world

Link
https://doi.org/10.1177/1756285617722706
Tags
Multiple SkleroseMS Behandlung
Jahr
2017
Autoren
Ziemssen T, Thomas K.
Verlag
Ther Adv Neurol Disord 2017;10(10):343-359.
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