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Sherlock-MS-Blog

Records of the neurodetective  
in the fight against multiple sclerosis


Articles

The brain’s early whisper

The brain’s early whisper

Before anyone says “MS?”, the nervous system is already whispering ...
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The Brain’s Janitors

The Brain’s Janitors

Metabolism. When you don’t know whom to suspect – it’s almost always metabolism. ⚙️🍽️
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The Double Case of the Season

The Double Case of the Season

Vaccines aren’t extras, they work undercover. In oncology, they boost the good – waking the neighborhood so therapy can aim true. In neurology, they dampen the bad – catching sparks before they ignite.
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Crime scene: Gray matter

Crime scene: Gray matter

In front of me is a fresh piece of evidence: a paper in Science Translational Medicine 📄🧪 about a new crime-scene method in MS—SV2A-PET with [18F]UCB-H. A radioactive mini-tracer that attaches to synapses and makes them visible on PET 🔦🧠. A flashlight for the contact points between nerve cells 🔌.
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The Neurological Identity

The Neurological Identity

Während ich über das so eben gelesene Paper zur Kernidentität des Neurologen von Joseph E. Safdieh und Mathew Stuart Robbins nachdenke, spüre ich förmlich den freundlichen Schlag auf die Stirn. Wir alle verlieren uns zu gern in unseren schönen Nischen – ich als begnadeter MS-Spurensucher voran – und vergessen dabei, was uns eigentlich ausmacht: Ana...
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The Watchman Who Wanted Too Much – TIM-3 Under Suspicion🕵️

The Watchman Who Wanted Too Much – TIM-3 Under Suspicion🕵️

In the brain, dear readers, there’s more than just neurons. There’s a kind of internal task force: the microglia. Think of them as garbage collectors, firefighters, and traffic cops all in one. When something breaks, they clean up. When inflammation arises, they step in. But – as with any police force – too much action can cause collateral damage. ...
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